THE MAGIC

(PSILOCYBIN)

MUSHROOM INTERACTION CHECKER

Reports arrive within a minute or two. Please check your spam folder – although sometimes a firewall will block reports even from reaching a spam folder. If you haven’t received your report, let us know via the Feedback button at the bottom of this site or email info@psychedelicinteraction.com and we will securely email the report directly to you within 24 hours, often within an hour or two.

Yes. We are building out a package and subscription option, and we anticipate their availability in the first quarter of 2025. For subscriptions, we are offering a 20% discount for those who subscribe within the first 30 days of go-live.

If you would like to be informed as soon as these options go live, please sign up here. We’ll let you know and send you a discount code!

Yes. We want you to be satisfied! But if you’re not, we’d like to make things right. Please inform us of your issue via the Feedback button at the bottom of the site, and include your name and email. If we can’t fix the issue or meet your needs, we’re happy to issue a refund.

The interaction report comes attached as a PDF via secure email. It goes to the email address you enter above. The email is discreet and does not mention the nature of the interaction report. The sender of the email will appear as “Interaction Checker” and the subject will read “Your Interaction Report is Attached”.

FUTURE REPORT ACCESS VIA SUBSCRIPTIONS AND REPORT PACKAGES:

When subscriptions become available: you will have a login with your own account dashboard where the interaction reports arrive and can be downloaded as often as you need for up to 30 days after report generation. You will also have the option to send the report to an email address at the time you generate the report, and it will arrive as per above.

When pre-paid discount packages become available: a set of interaction reports can be pre-purchased for a single user (i.e. just you, the account user, will later generate the reports) or for multiple users (i.e. the pre-paid reports are later generated by others–for example, retreat centers or churches pre-pay for reports which are generated/redeemed with a voucher code by participants). In the single user case, reports will arrive in your account dashboard and can be downloaded as often as needed for up to 30 days after report generation. You will also have the option to send the report to an email address at the time you generate the report–and it will arrive as per above. In the multiple user case, the reports redeemed/generated by others will go to the email address they enter–and the report will arrive as per above. For HIPAA compliance with multiple users of a report package, no interaction reports or emails of voucher users will appear in purchaser’s account dashboard. However, voucher ID with timestamp and type of report pulled will be displayed.

You might be thinking this information should be free, or scratching your head about why we don’t charge more. Either way, we believe the information we provide is valuable. Thousands of expert hours and personal resources went into this tool. There were no private equity or venture capital dollars attached to the creation of this tool. While we recoup our own costs and hopefully make a little extra, we consider it just as important to make the information affordable, unbiased and high quality for our users. We thought about the costs of specialist copays, primary care copays, Medicaid & Medicare copays, and the cost of a medium coffee (our favorite drug!) before we landed on our cost tiers.

If we get enough support, we would like to be able to make the basic report available for free.

Dr. Kristin Speer (she/her), PharmD, BCPS, is a Colorado-licensed pharmacist who created and owns this tool. Please refer to her full bio linked on the site for more details. To help maintain the interaction database, she established a small team of pharmacists who hold expertise in psychedelic pharmacology, drug interactions, and evidence searching & evaluation. Dr. Speer is one of the founders and board directors of the Psychedelic Pharmacists Association. However, the tool is not currently affiliated with the Association.

No AI went into the creation of this tool.

As licensed healthcare professionals we understand and strictly observe HIPAA and other healthcare regulations. More importantly, we deeply respect your need and concerns for confidentiality and wish to uphold your trust. This is why we use military-grade (AES 256-bit) encryption and ask for the minimum amount of information to generate and send the report. (Besides, we wouldn’t know if the meds and email you enter are yours or someone else’s anyway!)

Yes. We are providing education for harm reduction purposes. Providing education to reduce potential risks and improve safety (just like with opioids, marijuana and other substances) are legitimate and professional activities. This resource is not to condone or encourage the use of illicit substances where they are illegal. We do not sell substances. 

Check that you’ve correctly spelled the medication. 

Try searching by both generic and brand names. 

If it’s a combination medication, try searching by other active drug names contained in the medication. 

If still no luck, it is possible your medication is not yet listed. We would love to know this so we can research and add what our users need! Please provide the medication name via the Feedback button at the bottom of our site and we will work as quickly as possible to research and add it. 

Check back regularly as we regularly update our database!

While the evidence supporting many interactions with psilocybin is limited, it is growing rapidly. Some interactions have stronger and better quality evidence than others.

When the risk of a medication’s use with psilocybin appears more likely and serious, we estimate the overall interaction risk to be relatively higher. These are assigned “moderate”, “moderate to high” or “high” risk estimates. When no interactions are found/expected, or interactions are not considered serious, or they are potentially serious but rare, these are assigned “low” or “low to moderate” risk estimates.

Please note reported interactions, like all drug interactions, are not guaranteed to happen, nor do they never happen. Nearly all drug interactions–including those reported outside of this tool–are predicted possibilities which can be impacted by additional risk factors, and they can change based on available clinical evidence and pharmacology data.

Our team updates interaction content whenever more robust and reliable evidence becomes available. We have established a system to continually monitor and evaluate published evidence. We review and use mainly primary and secondary sources of literature, but include some tertiary sources when applicable and appropriate. 

There are few human studies that look at real outcomes of taking psilocybin and specific medications together. For this reason, reactions and outcomes from a combination (interaction) may be determined from evidence-based pharmacology and adverse effects that overlap or interfere with each other. Evidence-based pharmacology and adverse effects are published in many sources–FDA labeling is one example. However, we do not cite these sources since this information is widely available and does not include psilocybin interaction data. Instead, we include citations when the literature specifically relates to an interaction with psilocybin or classic psychedelics. If you’d like the source we used that lists a medication’s pharmacology or adverse effect, please reach out via the Feedback button on our site and we’ll send it to you!

Yes, the report distinguishes whether the interaction applies to MACRO-doses and/or MICRO-doses. If the report does not specify what type of dose (i.e. it just says “psilocybin”), then the interaction or information applies regardless of psilocybin dose.

No. This tool does not check for interactions between your medications. It is important to consult a pharmacist or your provider on the current interaction risks between all your medications before taking psilocybin. This tool reports on interactions between psilocybin and your medications. Also keep in mind that it’s possible for psilocybin to carry a particular risk with each individual medication you take, but adding psilocybin to the whole mix can increase overall risk.

If you count brand names, there are about 600 different search options on this site.

There are currently over 200 of the most commonly used generic prescription medications. There are some common supplements and other substances, too. We are constantly working to add more. If you don’t see yours, let us know via the feedback button at the bottom of the site and we’ll add it as quickly as possible!

No. Please see our disclaimer. Medication interactions are based on outpatient or community use (i.e. formulations and uses outside of a hospital or urgent/acute settings.)

Yes. A minimum of 5% of profits go to Indigenous communities in Colorado.

Not currently. Due to psilocybin’s popularity, accessibility and inclusion in many state drug reform initiatives, we decided to start with it first. Depending on demand, feedback and other factors, we may add reports for DMT/ayahuasca, 5-MeO-DMT, LSD, MDMA, ibogaine, mescaline/peyote, etc.

We want to know! Please notify us via the Feedback button at the bottom of our site. Please include relevant details about the issue. For report issues, it will help to include the email address where the report was sent so we can research the content that was sent.

Please submit your question via the Feedback button at the bottom of our site. We will do our best to get back to you in a timely manner. Please note we cannot provide interaction details via the Feedback feature or direct email. We do not provide consultation services at this time.